Everyone who attempted to manipulate Sasuke failed in a very poetic way.I mean you can hate him but Itachi is just broken. That magic AIDS hindered him more than the sharingan Kakashi has.
If anything, Itachi being revamped into a hidden hero is ridiculous. Sasuke gets easily manipulated into whatever.
When you put it that way, I can't deny that. Very good point.Everyone who attempted to manipulate Sasuke failed in a very poetic way.
Orochimaru tried to groom him into becoming his vessel, only to find out that he was being used and get absorbed by Sasuke instead.
Itachi tried to manipulate Sasuke into becoming a hero (through really messed up ways), Sasuke joined the Akatsuki and threaten to annihilate the village instead, making Itachi's whole lifework go in vain.
Obito tried to manipulate him into becoming the Akatsuki's powerhouse and capture Naruto, Sasuke turned the tide of the war against him and his downfall was at his hand, Ironically, side by side with Naruto.
Kabuto and Madara also briefly tried to manipulate him into joining their side.
If anything, Sasuke is the hardest to manipulate. Look how much effort it took Naruto to sway him.