Proof that it is possible; In part 1 Akamaru was seen ingesting soldier pills. The effects of which greatly boosted his abilities, granted him access to new abilities and jutsu, and turned his body red. Link:
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Yes, I'm about to dope my animals. No, please do not call the RSPCA on me.
Yin, Yang, Med in inventory;
https://animebase.me/members/telie.70437/#dbtech-shop-inventory
Referenced Technique:
Spectral Sense
Name Of Medicine: Duality: Sun and Moon Divine Dan
Creator: I, Scaze! (uh, Telie)
Type: Supplementary
Description and Background: The Duality: Sun and Moon Divine Dan was developed to unlock the latent potential of a Ninken and, at higher dosages, enable a Ninken to entirely transcend their limits and access newlyfound powers. True to its name, The Duality Dan comes in two forms; a medium of ginseng root, turtle shell, oxen bone marrow and snake blood is crushed, purified through sublimation, chemically combined through heat and chakra, and finally infused with vast amounts of either Yin or Yang chakras. The resultant powder is then encased in a rudimentary capsule to create a rather potent set of pills.
The pills produce three stages of effects, dependant on their dosage, growing progressively stronger at each stage. At the first stage, pills will primarily produce enhancements to the body or chakra systems of the recipient - yang the body, yin their chakra - respectively. The second stage will greatly affect both body and chakra, and the third stage will shift the effects from enhancements that primarily affect the self, to enabling access to phenomena capable of impacting the external world.
Stage 1 of the Duality: Sun and Moon Divine Dan:
Sun Pill: Ingestion surges Yang chakra throughout the body, unlocking the latent physical potential of Ninken physiology. With musculature enhanced to the peak, and efficiency of neural pathways increased by surging chakra, Ninken who have ingested the Yang pill will gain a +30 boost to their Inuzuka techniques and physical attacks. Heightened physicality will also allow them to extend the potential of Inuzuka techniques, increasing the range of Gatsuuga's, Gatenga's and Inuzaka attacks by one.
Moon Pill: Ingestion surges Yin chakra throughout the chakra system, unlocking the latent chakra control potential of Ninken physiology. With spiritual and mental control pushed to the peak, and mental awareness of chakra pathways expanded, Ninken who have ingested the Yin pill can passively silence their chakra and energies, which would typically leak out and be detectable by sensors, thereby rendering them sensable only through normal means (basic senses, not 6th senses like chakra, emotion, vitality or w.e sensing). This embodies the role of Canines as apex hunters - pushing their stalking capabilities to a new peak as necessitated by a world of ninjutsu. Greater chakra control also allots for passive activation of the Ninken unique sensory technique, Spectral Senses.
Stage 2 of the Duality: Sun and Moon Divine Dan:
Sun Pill: Affects Ninken physiology in full; this time a Ninken will experience a 2.5x speed increase, and their body will leak a shroud of overflowing yang chakra. This overflow will make their physical attacks more potent, allowing them to produce B ranked damage with their free-form attacks, and finally, similar to white tiger, their physical and Inuzuka based attacks will produce an imbalance in the chakra of struck enemies. Victims will have to expend 1.5x the chakra to perform techniques, increased to a maximum of 2.5x for each successive attack landed. (Each two additional attacks increases expenditure by 0.5, and like White Tiger can be countered through senjutsu, yin, yang, and y/y surges of greater chakra. Starts as a B rank effect with each successive strike adding 10 chakra and increasing the surge demand respectively.)
Moon Pill: Affects Ninken physiology in full; affected are capable of shedding their physical forms and converting to a spiritual one, not at all unlike hands of sloth. Spiritual form renders a Ninken intangible, and completely incapable of interacting with physical structures or techniques - instead they freely phase through space along the Y, X and Z axis. Due to their intangibility, their attacks will deal spiritual damage, but naturally they and their attacks will still be fully visible. It costs a move to enter this form, but not leave it, and it can only be sustained for a maximum of three turns.
Stage 3 of the Duality: Sun and Moon Divine Dan:
Extending beyond empowerment to the self, the third stage allows a Ninken to harness the injected energies and, combined with their own, project new entities - the Komainu and Inugami - out into reality. Based on Yin and Yang respectively, the Inugami allows for the materialisation of independent spiritual familiars of Yin, and the Komainu physical - to the point of living flesh and blood - materialisation. True to Inuzuka techniques, these dog like projections can range in appearance from natural breeds, to canines of demonic and mythical variations (additional heads, limbs, etc etc), ranging from either normal sizes to giant summon sizes, created either around the Ninken or projected externally (within short range). With a base damage of 100, the created familiar will deal either physical or spiritual damage accordingly, however from the turn after their creation their free-form attacks, which carry damage equal to the full might of the projection, will cost a move. Similarly, Inugami can phase through constructs, however they must be made tangible to attack and are visible in either forms (can passively switch between), while the Komainu is created with physical abilities that match a Ninken under the effects of stage 2.
Description of Side Effects:
Biographies that possess this pill start battle with 600 less chakra (additionally, the bonus chakra from the Yang speciality, if the user has it, is halved): This is because by default these pills have an extremely short shelf life, but are exhausting to manufacture on account of the vast amounts of Yin and Yang Chakra required. This is to such an extent that even after rest, the creator will not have recovered completely. However, a short shelf life requires an Inuzuka to constantly subject themselves to this process to keep a stock, as the pills react negatively to preservation methods (chemical, physical such as freezing, etc). Must be posted at either the start of the battle or in the users biography, and it does not reduce the Inuzuka's total max chakra, just chakra available at battle start.
Stage 1: lasts for up to five turns. Once pill effects end, the strain to either the chakra system or body produces small lacerations within a Ninken's muscles that reduce the power of future Inuzuka techniques by -30 (Yang pill). Or, physically frayed chakra pathways that require the expenditure of an additional 20 chakra (with no added effects) to perform further techniques (Yin pill) - These effects last until healed, or until five turns pass, whichever comes first.
Stage 2: lasts for up to four turns. Once pill effects end, the overclocking strain damages the skeletal structure - leaving it compromised from multiple hairline fractures and thereby halving their speed, they also experienced frayed chakra pathways that increase their required chakra expenditure by 1.5 (yang). For Yin, chakra pathways will become physically contorted and compressed at intermittent intervals throughout the body due to flesh that has been internally warped and disfigured - this leads to an inefficiency that requires 2x chakra expenditure to perform techniques and reduces the power of such by -20. These drawbacks last until these wounds are healed.
Stage 3:
Replaces the Inuzuka's usages of the canon "Eight Branched Giant Snake" and "Hands of Sloth"
A Ninken currently manifesting a Komainu or Inugami cannot perform further techniques, instead a Komainu or Inugami will adopt their traits and thereby perform Inuzuka techniques in the Ninkens stead.
When a Komainu or Inugami is destroyed, a Ninken will suffer physical or mental backlash (respectively) equal to the number difference between the destroyed Komainu or Inugami, and the technique that destroyed it. (For example, if a 100 dmg Komainu is destroyed by a 140 damage technique, the Ninken will immediately experience a 40 damage backlash in addition to having to deal with the remnants of the incoming attack.)
A Ninken can consume a stage 3 pill once, after which they must wait three turns to consume any pill again, regardless of how much their Inuzuka heals them. Komainu and Inugami cost 70 chakra to create, and are not meant to expire, however the effects of the pill do, wearing off after four turns and with that, the Komainu and Inugami dissipate. Inversely, backlash damage from the destruction of a Komainu or Inugami neutralises the effects of a stage 3 pill.
Additional notes and restrictions:
Crude and rudimentary, pills unlock higher stages simply through a multiplicative increase in dosage - this also means that the beneficial effects and drawback sides of each stage stack. Any stage can be entered at any time, in accordance with the dosage, however there are limitations on usage. A Ninken can consume a stage 1 and 2 pills twice each, with no cooldown, however consuming a pill without having recovered from the side effects of the last one will half the beneficial effects and increase the sides by 50% (diminishing returns)
There is nothing stopping a Ninken from consuming both a Yang or Yin pill, however attempts at such by default will heavily damage a Ninken's internals and leave them comatose after only two turns. This is due to the introduction of two conflicting energies, which quickly overloads into a pseudo 'poison' that attacks a Ninken's vitals. Even consuming a Yang pill while remnants of a Yin pill remain within ones system (or vice versa) will lead to this negative effect - and it typically takes fifteen turns for a pill to completely clear from a Ninken's system. Ninken rendered comatose cannot consume further pills even when healed. (until the arc ends)
Ingestion of these pills and their subsequent effects are passive, and their effects kick-in immediately. However, feeding them to a Ninken is a freeform action, much like throwing a Kunai (or whatever), that could logically be interrupted. Creation of a Komainu or Inugami counts as a move, adopting a Spiritual form in stage 2 also costs a move, but can be entered and exited freely once activated for the duration of the pill.
Stage 1 requires one pill, stage 2 two pills, and stage 3 four pills to be consumed at once. Consuming additional pills is considered a pointless overdose as it has yet to lead to the observation of additional beneficial effects. By default, the user possesses an inventory of 15 pills, however this can be increased to a maximum of 30 pills at the cost of starting battle with a further -20 less chakra per additional pill. (in the NW pill stock and consumption regenerates at a rate of 5/week, but still with the associated chakra costs, and while replenishing, chakra regeneration is halved.)
At any stage, a bite from a Sun and Moon enhanced Ninken will drain vitality (Sun) or chakra (Moon) at a rate of 50/100 a turn. By default this is only effective on enemy Shinobi, or summons (Returns for the latter are halved).
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Depending on how this goes, I'm willing for my Inuzuka to suffer some restriction, or even complete denial, to the access of Yin State and Yang State, too.
Declined DNR. Something like this was tried before by Delta, here. The consensus is medicine can only be used by shinobi.
Checked by @Howard