Guys. guys. Tsukyomi works given the extent of the chakra flow that the user does it in the enemy system. On someone normal who doesn't have Sharingan and who doesn't possess the skills that Tsunade has, it works, but given her mastery in the human body, it won't.
Let me explain you why.
What does Tsukuyomi do? It takes your chakra which flow throught the tubes that are connected to your cells and through shock waves it sends different commands to your brain.
Mind is working dependable on how the brain works. If your shock waves dictate you to jump in one feet in your mind you jump in one feet, because these are the signals your brain is receiving.
Genjutsu (generally speaking, meaning it includes them all, even Tsukuyomi) is created when a ninja extends their chakra flow through the cerebral nervous system of their opponent to control their minds chakra, thereby affecting their five senses. Genjutsu techniques manipulate the flow of chakra in the victim's brain, thus causing a disruption in their senses.
Who has been showed to fix these irregularities if not Tsunade, as I said up there? Given her technique, any type of damage done to her brain in order to do damage to the body, given the techique it would be impossible because it would counter it. Basically any damage that comes, either mental or pshysical, the jutsu will make it ineffective. It's a link between the jutsu and the body. As in the technique is programmed to heal/resolve any irregularities that it feels in connection to the body.
