Blood is blood. Sasuke's body is quite different from Indra's. And therefore weaker.
That's why Salad and Izumi are passing out.
Even they had great chakra, their body wouldn't sustain it.
This is not the case although Sasuke's genes are varied Indra still transmigrated into him. Indra's chakra is manifested in his body and is passed onto his descendants(not the Indra soul). Just as the Uchiha clan inherited his powerful chakra, spirtual energy and eyes. As for the excuse of bodies not being able to sustain great chakra that's nonsense since the Indra gene exists in their blood (hence bloodline and other abilities).
Izumi did. In fact, she passed out.
Kakashi is just an exception. He didn't even have a clan.
Izumi didn't pass out from being 1/2 anything that's fanfic unless it's been stated as such.
Why would Kakashi a non Uchiha with average chakra reserves be an exception. He's got nothing special going for him to make him exceptional.
Inheriting his talent =/= Inheriting his chakra
You can't have the talent or benefit from it if you don't have the abilty to do the same, one is contingent on the other. It's like saying such and such has inherited his fathers talent, the father is a world class high jumper, the child would need the ability and the gentic material to be able to produce the sams results otherwise he doesn't have the talent. Anyway the Uchiha inherited the sage's dojutsu, chakra and spirtual energy. According to the manga strong chakra gene and exceptional chakra is a clan thing. Even Itachi with his aids and below average chakra due to it was able to pull of chakra taxing feats including always having an active Sharingan.
The Boruto anime especailly last 2 episodes were blatant nerfing especially when conpared to her previous chakra use.