I don't think Orochimaru is scared of anyone tbh. when itachi schooled him the first time, he marvelled at the uchiha's power. When he saw 4-tails naruto he was enetertained. And he showed no fear when he faced Itachi a second time. If anything, his overwhelming arrogance was his downfall all times.
The only time he showed fear was when Hiruzen took away his arms, and when sasuke absorbed him.
The only time he showed fear was when Hiruzen took away his arms, and when sasuke absorbed him.