I love all the responses that are saying how the Uchiha are the best, Uchiha are #1, etc. even though they're extinct. There's not even an Uchiha clan anymore. Just some Uchiha stragglers. But don't get me wrong, any one of those stragglers would rape the sh*t out of any Hyuga.
Well the uzumaki clan is, for the most part, dead, and the hyuuga are simply irrelevant to the plot. They are both very powerful, but the uchiha and senju rivalry is of main concern to kishi.
just read the argument i used and if u have a refute lets hear it
Stop This Planet , I Wanna get Down.
Itachi didn't have ems only ms so how many times can he use amaterasu if the hyuga is running like hell and lets see if he uses susano the hyuga can counter his almighty sword with rotation and how long can he keep it up without going blind or running out of chakra he also cant use his eye genjutsu because the hyuga's aren't focused on his eyes rather his chakra flow u r very knowledgeable but in just neji versus itachi i would go with neji because itachi only has MS not EMS(which only prevents blindness doesn't grant user infinite chakra) and if the fight starts out while itachi is in range of 64 palms it will be over b4 it begins
hyuga are better in taijutsu.......
i think hyuga beat uchiha