1. Itachi doesn't need to use his eyes to place someone in a genjutsu. He has other options like izanagi,izanami, finger genjutsu and conventional genjutsu
2. Not everyone can fight by not looking into someone's eyes. The only exception was Gai and this was mentioned back in p1.
3. You can't separate a user from his own chakra. This was debunked in the war arc, minato can't separate someone from susanoo. Ftg is chakra signature linked
4. Minato can only move to a location is seals are at. Bee noticed that in an instant and I'm sure Itachi is a thousand times smarter than Bee will realize this to
5. Minatos strongest abilities all get tanked by susanoo
6. Genjutsu in a fight with Itachi is inevitable
7. Itachi was capable of keeping up with Kcm naruto so minatos speed is not a problem at all
1.- Other Genjutsus that aint Tsukuyomi wont affect Minato. He is very great at chakra control and a Sensor. Izanami only works with those who lost path and Izanagi. Minato is a sensor and Itachi cant catch him off guard.
2.- Gai is not the only exception. There was war between clans such as Uchihas and Senjus where Hashirama and Tobirama survived and something they have different from other is that both are
SENSORS. No wonder why they could fight Uchihas. Minato is a better sensor than Hashirama.
3.- In fact, this was affirmed in the war. Minato can link his chakra with someone's chakra. Susano is the chakra form the user. Minato touches the Susano and links to the User. Minato can decide what to take and what to leave.
4.- Raikage was the one who knew this. By the war, even knowing this, will all the speed he has, could catch Minato. Someone thousand times slower also wouldnt.
5.- Itachi's attack wont hit Minato. Minato does not need to hit Itachi, just touch him once and it is over. I already said said why Susano is a big disadvantage here besides its high chakra cost for Itachi. With a mere Kunai to head is enough.
6.- Speedblitz in a fight with Minato is inevitable. In fact, the first to hit might win.
7.- Itachi was not able to keep up with Blood lusted Naruto rather a Naruto who just keeping up with Itachi in order to change info.