the hyuga won't be able to make contact if an uchiha uses susano'o, and they'd need to concentrate on the susano'o as well as the uchiha as they both move differently, all the while the uchiha can still attack with genjutsu, kamui and maybe amaterasu, taking into consideration the hyuga's defense...but their defense can't fend against something that isn't physical...and if you use that sword that itachi's susano'o had it would also bypass their defense.
one on one, talented ninjas, the uchiha would win.
untalented, still uchiha cus they'd still predict their moves to be able to dodge them and keep out of range, the byakugan is for reading chakra not movement.
clan vs clan, probably hyuga because they have a lot more and the uchiha is near gone.
i would exclude madara as he isn't a typical or 'simply talented' uchiha....he doesn't share the same dojutsu and he has his own unique abilities...but if we do include him then the results the same.
the reason why in the manga they said that the byakugan was stronger than sharingan was because they weren't referring to mangyeko sharingan...