Orochimaru was obsessed with Hagoromo's descendants because he didn't have their natural talent that's a fact that cannot be denied.
1. He failed at learning SM
2. He relied on thousands of experiments to develop his own jutsu
Tobirama, Naruto, Hashirama, Kushina all possessed demi-god tier feats because of their natural talent, something Oro lacked.
Inb4 "but he was a prodigy" statements, yes he was indeed one of the most talented prodigies by non-Otsutsuki standards, but compared to Otsutsuki descendants he was nowhere near their level, manga scan for proof
Tobirama's talent for jutsu was far superior to Orochimaru, hence why Oro admired him so much
1. He failed at learning SM
2. He relied on thousands of experiments to develop his own jutsu
Tobirama, Naruto, Hashirama, Kushina all possessed demi-god tier feats because of their natural talent, something Oro lacked.
Inb4 "but he was a prodigy" statements, yes he was indeed one of the most talented prodigies by non-Otsutsuki standards, but compared to Otsutsuki descendants he was nowhere near their level, manga scan for proof
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Tobirama's talent for jutsu was far superior to Orochimaru, hence why Oro admired him so much