Itachi: One of the most gifted and well rounded shinobi in the entire manga. Represents the "hero" theme that is prevalent in today's society well. Think about guys like LeBron James or John Cena. People love those who have the tools to be considered the best at what they do but the humbleness that keeps them from feeling better than anyone else. In other words it's best to be strong and say you're not. Itachi's background story is one of sacrifice, secrecy, complexity and love. The role of the tormented hero who had to shoulder a major burden for the better of those around him is played very well by him. He was ridiculed, hated, and shamed by the very people who he himself ultimately died to protect. In a way his character carries similar undertones to the background of Jesus Christ. Itachi is good to those who like him because they like him, not because he tells them.
Minato: Another well rounded character with the "hero" factor. While he may not have the versatility of an Itachi, he is still very equip in many areas. What's also notable is he is one of the strongest characters in the series to belong to a non-hyped clan, a true testament to his strength and skill. In other words Minato is gifted despite being gifted. His background story is also one of sacrifice and trial. It doesn't contain the element of hatred that Itachi's does, however, many of Minato's fans like him for the admiration and respect he has garnered from everyone that knew of him. As strong and ominous as he was originally portrayed to be, the real Minato is a simple loving father and husband with a warm personality. He sacrificed his life for the village, and even gave his son to protect the villagers. While many do not approve of what he did with Naruto, others acknowledge that Minato did indeed love his son very much and in the end saved his son's life, His sacrifice of making his son the jinchuriki of his village is similar to that of how God gave his son to the world to be their savior and symbol of salvation