Very well then.
Manda can tank it since it tanked Deidara's C0 which is way stronger than Jiraiya's Katon. Tsunade would have to get past about a thousand snakes all of which have the Kusanagi no Tsurugi and poison.
Lets not forget in the databook Orochimaru has a 5 in handseals while Jiraiya has 4.5 and Tsunade has 4. Orochimaru and Jiraiya have a 4.5 in speed while Tsunade has 3. So Orochimaru is the fastest when it comes to weaving handseals and is tied with Jiraiya in foot speed. Tsunade, the slowest out of the three in both foot speed and handseal speed, stopping Orochimaru from weaving four handseals and clapping is unlikely especially when he has 1000 snakes and Manda with him.
Manda didn't really tank Deidera's attack....for one, it killed him, and he wasn't even hit with the full brunt of the blast.
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He clearly says "Part of the blast" If they had been there any longer, Manda would be in pieces along with Sasuke. Manda is a strong summon but he's not THAT powerful.
If you actually think manda is going to tank this
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you're nuts. Manda would get toasted...Jiraiya is capable of using some of the most powerful fire release techniques we've seen besides Amaterasu, not to mention in sage mode his katon is boosted by pa's fuuton.
I'd say in sage mode Jiraiya is faster than Orochimaru.
I'd say Orochimaru is the most powerful because of edo tensei. However, without edo tensei he would lose to SM Jiraiya IMO. Tsunade is mainly a medical ninja....she is strong but her skill-set isn't really catered to 1v1 combat. .
Honestly I consider Edo Tensei pretty hax especially when you're talking about a 1v1. However the fact remains that Orochimaru can use it to summon powerful past ninja to fight alongside him. When you really get down to it, Edo Tensei users will win almost any 1v1, as no one can take on a kage level ninja + countless kage level summons, except for Madara or Hashirama.