At the moment i can only think of these five, but if you know any, feel free to put your input 
jaraiya: lost his comrade and watch him betray the leaf as he try to bring him back
kakashi: his stubbornness cost him his friends life and visits the grave every often
naruto: born with a distructive fox spirit that had him shunned from the villages love
sasuke: lives with the thought that his clan was massacred by his brother
itachi: killed off clan except his little brother and then exiled himself from the very village he tried to protect
your input: (could be a ninja from any village)
my vote is kakashi. i feel that his life was tough right after obito died (really because he visits grave every so ofter)
whos your pick :lili:
jaraiya: lost his comrade and watch him betray the leaf as he try to bring him back
kakashi: his stubbornness cost him his friends life and visits the grave every often
naruto: born with a distructive fox spirit that had him shunned from the villages love
sasuke: lives with the thought that his clan was massacred by his brother
itachi: killed off clan except his little brother and then exiled himself from the very village he tried to protect
your input: (could be a ninja from any village)
my vote is kakashi. i feel that his life was tough right after obito died (really because he visits grave every so ofter)
whos your pick :lili: