During his time in the Academy, Lee proved to have no talent for ninjutsu and genjutsu. When he was mocked by his peers because of this, Lee persevered, focusing on taijutsu. After he succeeded in graduating he was added to Team Guy along with Neji Hyūga and Tenten. During the team's first meeting, Lee vowed to become a powerful ninja without using ninjutsu or genjutsu. Neji laughed at him, but their sensei, Might Guy, took a special interest in Lee. He encouraged Lee to keep at it and, in time, began teaching him powerful forms of taijutsu.
Having not been allowed to participate the year before, Team Guy took part in the Chūnin Exams along with the Rookie Nine. They initially tried to avoid attention by acting weak, but Lee accidentally let slip his true strength by interfering with a fight between Sasuke Uchiha and Kotetsu Hagane. He also fell in love with Sakura Haruno. Soon afterwards, he confronted Sasuke, challenging him to a fight to see how he fared against the Sharingan, but not before knocking out Naruto Uzumaki, who tried to fight with Lee himself. Guy interrupted Lee and Sasuke's fight, however, when Lee tried to use the Front Lotus, and Lee was forced to do laps around the practice range before he could proceed onto the first phase of the exams. With Tenten's help, he gained the answers for the written portion, and proceeded to the second round.
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After spending their first few days in the Forest of Death gathering supplies, Team Guy split up in search of other teams. Lee came across Sakura being attacked by Team Dosu, and went to her aid. He used his Front Lotus on Dosu Kinuta, but he survived the attack because of Zaku Abumi using his Decapitating Air Wave in the ground, and Lee was left unable to defend himself from a counterattack from Dosu. Neji and Tenten soon arrived to help, but didn't have to because Sasuke woke up, and once he recovered they moved onto the preliminaries.
In the preliminaries, Lee was matched against Gaara. When his standard attacks proved unable to bypass Gaara's defences, he removed his ankle weights to increase his speed and managed to land a couple of hits on Gaara. Then, he attempted the Forward Lotus, but Gaara was able to escape at the last minute revealing a sand clone instead. His options running out if he was to win and prove himself, Guy allowed him to use the Reverse Lotus. Gaara barely survived by turning his gourd to sand to cushion him, and the techniques took a massive toll on Lee's body. Gaara added to Lee's injury by crushing his left arm and leg. Though Guy intervened to stop Gaara from killing him, Lee got to his feet to continue the battle, despite being completely unconscious.
Because of his injuries, medics predicted, that even if Lee recovered, his injuries would prevent him from ever being able to be a shinobi again. He nevertheless tried to train while he was in the hospital, something that only worsened his condition. When he was asleep, Gaara came to his room and tried to kill him, but he was stopped by Naruto and Shikamaru Nara and later by Guy. To try and cheer Lee up, Guy took him to watch the final round matches, but they were surprised when they arrived to find out that Neji had been defeated by Naruto. Envious of Naruto, Lee then watched Gaara's fight with Sasuke, and marvelled at how quickly he had learned to emulate Lee's speed. Before the fight could finish, however, the invasion of Konoha began, and Lee was knocked unconscious.
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Lee can be seen at the Third Hokage's funeral alongside the other villagers, mourning his death.
Over the coming weeks, Guy tried a number of his own remedies to heal Lee, though none of his efforts worked. It was not until news of Tsunade becoming Hokage reached them that they found hope. But, when she examined Lee, she informed him of the dire situation: his broken bones and torn muscles have healed, but fragments of bone had lodged in his spinal column, and removing them would involve an extensive operation that only she was capable of. When Tsunade offered him an operation that carried a fifty percent chance of returning him to his former state, or dying in the process, Lee was hesitant to accept the operation. Though Lee was worried he would die in the operation, thanks to Guy's influence, he accepted the surgery. Upon overhearing Naruto, Chōji Akimichi, Kiba Inuzuka, and Shikamaru Nara talking about the mission to bring Sasuke back to Konoha, Lee suggested that Neji go with them. Lee was disappointed that he couldn't go with them, still needing to go through his surgery that was scheduled for later that day (In the anime, Lee was recovering after having his surgery done the day before). In the end, Lee successfully survived the operation.
Kimimaro vs Gaara Rock LeeThe final moments of the fight with Kimimaro.
Once Lee was well enough to move, he left the hospital to follow them and provide assistance. He caught up with Naruto, who was in the middle of a battle with Kimimaro, and told him to go after Sasuke while he dealt with Kimimaro. At first, it seemed Kimimaro overmatched him, but after Lee drank some sake that he had mistaken for his medicine, he began to outclass Kimimaro. Though Lee's anticipated moves were unpredictable to Kimimaro, he revealed his Kekkei Genkai, Shikotsumyaku, which, combined with Lee sobering up, easily took over the battle. Before his attack landed on Lee, Gaara arrived just in time to save him. Even though Lee insisted to fight side-by-side with him, he knew he was only getting in Gaara's way.
For the rest of the battle, Lee watches and is amazed by Gaara's new abilities. Even though Gaara's new techniques completely buried Kimimaro, Kimimaro counters by turning the battlefield into a forest of bones, which Lee and Gaara escaped by hanging onto a pair of small clouds made out of sand. Kimimaro then emerged from one of the bones, preparing to kill the two at point blank range. They were saved, however, as Kimimaro finally succumbed to his disease and died. After the battle, Lee and Gaara reflect upon Kimimaro's purpose, then the two return to Konoha.
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Team Kakashi was sent on a mission to rescue Gaara from Akatsuki. When Tsunade began to worry that they might have problems, she sent Team Guy as back-up. On their way to a rendezvous point, they were attacked by Kisame Hoshigaki. Kisame was quite angered that Guy didn't remember him from their fight in Part I. Kisame soon captured Lee, Neji, and Tenten, but by opening the sixth gate, Guy ended the fight quickly, and they moved on.
Once Kakashi's team arrived after them, the two squads found out that there was a barrier on the Akatsuki headquarters, something Team Guy volunteered to take down. They split up and removed seals spread out across the area, bringing down the barrier but triggering a trap: they were attacked by clones of themselves. When they were about to be defeated, Lee figured out how to beat the clones — by being stronger than when they met them. With that, Lee uses a new technique to defeat his clone. Later on Lee and the rest of his team-mates would confront Deidara who had been hiding and spying on Team Kakashi. With Deidara ultimately fleeing the scene and leaving an explosive clone behind, they are saved by Kakashi who warps the explosion away. Once Gaara was later revived, they headed back to Sunagakure and then later to Konoha. As they left, Guy had to carry Kakashi who had been incapacitated from using the Mangekō Sharingan too much. Seeing this as a form of training, Lee told Neji to get on his back so that they might race back to Konoha, but was forcefully rejected.
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Lee and the rest of Team Guy were only seen in the very beginning of this arc in the anime, as they returned from Suna. Lee, thinking he had come in second place in his and Guy's race from Suna to Konoha, was shocked when Guy informed him that since he was carrying Kakashi on his back as well, Lee had only come in third. Lee was seen carrying everyone's packs when they returned to Konoha. After escorting Kakashi to the hospital, Team Guy went to rest.
During Pain's invasion of Konoha, Team Guy was away on a mission. On their way returning to the village, they noticed a large number of birds flying from the direction of the village and rushed to see what the issue was. When they arrived to see the village in ruins they also spotted a severely wounded Hinata Hyūga, and got her medical attention. Later, Lee, alongside the other villagers, celebrated Naruto's victory over Pain.
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When news reaches Konoha of Sasuke Uchiha's crimes against other villages, Lee and the rest of the Konoha 11 decide they should eliminate Sasuke themselves before he can involve Konoha in a war. So that Sakura can inform Naruto of their decision, Lee, Kiba, and Sai escort her to the Land of Iron. When they locate him, Sakura tells Naruto that she loves him, surprising Lee. This does not convince him to give up his own search for Sasuke, so they leave without another word. Sakura then asks her escorts to help her find Sasuke. When they near his location, Sakura tries to knock them out so she can face Sasuke alone. Sai stops her, so Sakura convinces Lee and Kiba that he is a traitor. While they try to detain him, she succeeds in knocking them out.
Konoha 11 reunitedThe "Konoha 11" meet to discuss Sasuke.
After Sakura and the rest of Team 7 meet with Sasuke, they retrieve Lee and the others and return to Konoha. Lee is later seen with the rest of the Konoha 11 hearing Naruto's decision to take responsibility for Sasuke. Though they protested this action, Naruto firmly states that he would be the one to take care of Sasuke. Before leaving, he promises to tell them everything when the time was right.
Lee and his team-mates were sent to back up Team Kakashi who were investigating what was happening at The Hole located in the Tonika Village. During this mission, Lee and Guy confronted Naruto's berserk clone, and after opening the Fifth Gate alongside his mentor, was able to stave off the creature before it took on a pseudo-Nine-Tails form.
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During the Fourth Shinobi World War, Lee is assigned to the Third Division alongside Sakura and Guy. He is seen fretting over his sensei's condition while Sakura tries to heal him. When members of the Surprise Attack Division are attacked by the reincarnated shinobi, the Third Division arrives in time to intercept the attack. He is then seen along with the Third Division clashing against the reincarnated ninja. Upon Kakashi's orders, they group into a Manji Formation, Lee promises that no matter what he will protect Sakura; she however tells him to also be careful as last time Zabuza was able to penetrate the formation from its weak point; the centre. He and Guy later intercepted Haku's assault with the Leaf Coiling Whirlwind. In the anime, after the Seven Ninja Swordsmen of the Mist were summoned, Guy told Lee to chase after Pakura while he went after Gari. After a long day battling, Lee and the recuperates with his remaining division members as night falls.
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With the resumption of battle the next day, Lee sticks close to Sai who had been tasked with sealing the reincarnated Seven Ninja Swordsmen of the Mist. Lee tells Sai not to worry and just concentrate on the sealing while he would protect him. When Naruto's shadow clone arrives on the battlefield, Lee exclaims that with him here their numbers would increase. However, Naruto tells them that he wouldn't be able to perform the Shadow Clone Technique in his current state, so they'd have to defeat the new wave of White Zetsu Army clones with quality of techniques instead of quantity in numbers.
Later in the anime, the Third Division came across another reincarnated shinobi: Master Chen — a renown hero of Konohagakure who was thought to have died during the Third Shinobi World War. As Might Guy who is happy at the prospect on challenging such a famed taijutsu master, Konoha's Sublime Green Beast of Prey soon finds himself being forced on the defensive by the old man. A shinobi is able to break away from the battle and in his search for reinforcements, finds Rock Lee who rushes to Guy's aid. Seeing the legend he met once before as a genin before him, Lee reveals his history with Chen before engaging the legend in battle. Ultimately, Lee is able to counter Chen's Leaf Dragon God technique, using the One-Man Front Lotus which he had engineered to counter the rotation of the winds of the former. As Chen's immortal body disintegrates, he remembers the time when he had his own student who was incapable of using ninjutsu, and how he had died during the Third Shinobi World War. Finally letting go of his painful past and apologising to the young man for what he had said, the old master was able to break the summoning contract and his soul returns to the afterlife. Lee promises to Chen that he'll bring rice balls to his grave.
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After being informed by Inoichi from HQ that Naruto and B were fighting the "masked Madara", Lee and the rest of the Konoha 11 rush to his aid. As he runs, he spurred Sai — who was lamenting the fact that he could not use his Super Beast Imitating Drawing technique to get to Naruto faster — onwards telling him that now was the time to respond to the heroic efforts of those fighting Tobi.
Upon finally arriving at the battlefield, and seeing his mentor's state, Lee asked whether or not Guy had used the Daytime Tiger technique again. He later stood with the other members of the Allied Shinobi Forces as they prepared to face their opposition. Opening the Fifth Gate, Lee and his mentor prepare to attack the two Uchiha, but are buffeted by the force exerted by the now fully-matured Ten-Tails as it escaped the hole it had seemingly been trapped in. He is then seen with Guy and Tenten reacting to Neji's death. Tearfully holding his fallen team-mate's corpse, he was stopped by Guy who told him to keep his tears and hold onto the feelings Neji left them. Lee was then seen listening on as Naruto imparted comforting words to the Allied Forces.
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Thinking back on his time with Neji growing up and the conversations they had, Lee mused about something Neji had said to him. Having received chakra from Naruto, the now empowered Lee, respectfully closed his fallen comrade's eyes before joining the ranks of the other Allied shinobi. Charging forward with the Alliance, Lee signalled to Naruto that he would deal with Madara while he took care of Obito. With Guy giving him a boost, Lee propelled towards Madara and remorselessly bisected the Uchiha with a powerful kick, also destroying Madara's connection to the beast.
He would later stare in amazement at the red barrier that had been constructed around the Ten-Tails and listened on as Guy noted that only shinobi of Hokage-calibre were able to perform the Four Red Yang Formation technique. With the situation later turning grim as the Alliance was trapped in a barrier with a Tailed Beast Ball-firing tree, Lee and the other shinobi soon found themselves shrouded in the previous Version 1 mantles again. He and the other subsequently found themselves on the outside of the barrier, escaping the near-fatal attack thanks to Naruto and Minato's action.
The Ten-Tails transformed into its final form, the Shinju, and many shinobi were attacked but Lee was able to escape. Hashirama Senju had Ino Yamanaka everyone link-up telepathically, Lee being one of them. Hashirama's words fail to inspire anyone, but Naruto's senjutsu-enhanced Tailed Beast Mode combined with Ino's telepathy causes his emotions and personal memories to be transferred to everyone. Later he mobilised alongside his comrades when Naruto called out to them. Shocked when he was enveloped by Naruto's Tailed Beast Mode mantle, Lee was apprehensive about their strategy at first but ultimately launched an attack on Obito and was able to overwhelm his defence giving Naruto and Sasuke the opportunity to attack Obito directly. He and his comrades later aided Naruto in extracting the tailed beasts' chakra from Obito in order to stop the Shinju from blooming.