It would be a draw like Sakura vs Ino if they are both prime.
Tsunade have more battle experience than Sakura is a stupid argument, given Sakura intellegence feats over compensates for her lack of battle experience , this was literally stated during the chunnin exams written test. And this is how she was able to match sasori.
Also Sakuras jutsu execution is slightly faster than Tsunades, as she doesn't require handseals to release her byakugou and tsunade does.
In a canon fight, Sakura would probably pull out some genjutsu feat to win, as Kakashi predicted that's the only way to truely surpass Tsunade e