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No, you see you can apply the concept of human genes. Kaguya had a partner which triggered the birth Hagoromo and his brother.
This means that Hagoromo has a new set of genes that could only consist of Ashura and Indra's chakra and that is why Kaguya
could not awaken the Rinnegan since her genes are different from Hagoromo since Hagoromo's cells are already mixed by Kaguya and her partner... UNLESS IF KAGUYA GAVE BIRTH ASEXUALLY then that would be a different story
Even if Kaguya had a partner, it would be obvious, that Hagoromo would inherit some of her genes, even if it's 1%