I would say yes with genjutsu, plenty of time.
However the only time he's activated Susano'o was near his death, to destroy Chibaku-tensei( not sure if that's the right name of the attack) & to seal Edo-Nagato, and several times activating limbs during Kabuto fight.
The parts we've seen him encountering someone were when:
Kakashi/Kurenai/Gai/Asuma
Jiraiya/Naruto/Sasuke
Kakashi/Chiyo/Sakura/Naruto
Naruto ( implanted crow inside him )
Sasuke - used it used it this time
Edo-Nagato - used it this time
Kabuto - used it this time
sooooo 3/7 encounters, and the only time you see him spam Susano'o(activated for prolonged time) was (arguably during)Sasuke's fight and then Kabuto's. I don't see that as spamming. Though my statements and claims may not matter, still Itachi wasn't a predictable character to me. You may see him as one, but I've seen his battles comparing to Sasuke that he's a versatile and unpredictable ninja. No one even knew about Susano'o until he unleashed it, not to mention hiding Totsuka blade and Yata mirror in his possession.
