This is Tsunade (Grandmother)Mito Uzumaki

BluePhenix

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This is from Narutopedia:

The Senju clan (千手一族, Senju Ichizoku) was considered the strongest clan in the ninja world during the war-torn era before the founding of the hidden villages. Together with their rivals, the Uchiha clan, they were responsible for founding Konohagakure and making the village into what it is today. They are also distant relatives of the Uzumaki clan.

Here's the link :)

 

Olorin

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well theyre both uzumaki or at least part uzumaki so yes they are related but since tsunades grandma was an uzumaki it cant be anythig close
 
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only time will tell how close they are connected, but she seem to close enough to let Naruto call her granny and let him get away with alot in the vile and not lose her temper with him.
 

animals74

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Its possible that they are, but at the same time, a possible no.
Senju and Uzumaki are distant relatives.
Mito Uzumaki--->______----> Tsunade
Mito and Kushina are from the Uzumaki Clan.
Red hair is a common trait for uzumakis, and its likely that she was
from that clan.
I dont think they're so distant though,
Kushina same group with Mito, and mito is just the grandma of tsunade.
 
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