Fig.1 - Phylogenetics Tree of Life.
It seem that many fans said about this issue
Pls read competely and if you want to argue (someone always do..)
Nothing much was mentioned by Kishi (if you know, pls highlight)
Uchiha & Senju
Somehow, there are posts mentioned that this is true.
I would like to highlight on one thing
What we know of this issue was come from Madara/Obito words (mouth).
When Madara/Obito telling the tales to Naruto, Kakashi & Yamato.
Kakashi did said one thing about this. Not to say to anyone, until proven so.
So6P had 2 sons.
The older son, who inherited the Sage's "eyes" (his powerful chakra and spiritual energy),
The younger son, who inherited the Sage's "body" (his powerful will and physical energy).
The older son not happy with So6P decision on choosing the younger son as successor.
Hence older son - Uchiha / Hyuga.
the younder son - Senju / Uzumaki.
Only Uchiha & Senju was mentioned by Madara/Obito only.
That... will make alot of diffence in opinion.
There is another issue.
Uzumaki clan have RED hair gene.
Then why Madara had choosen Nagato Uzuamaki, because he had (Sage's body) and RED hair.
Also that Uzumaki village was totally destroyed.
That may proof that the Fig.1 is almost correct.
Also that Madara/Obito mentioned to Naruto/Kakashi/Yamato that the day were come,
that Naruto (Uzumaki's gene) will fight with Sasuke Uchiha gene.
As for the Bijuu, i do have something like this;
Bijuu is part of So6P
Why Minato put Kurama inside Naruto.
There is a strong reason for this, which Tsunade mentioned while Naruto & B go to battlefield.
The reason is that Naruto will have to deal with Madara/Obito.
Thanks for reading......................................