The Sannin take this.
1. Itachi already stated that him and kisame together are no match for jiraiya. And at best they would both die.
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2. Orochimaru in his prime is just NASTY!!. A handicapped oro was able to fight on equal footing with a 4 tailed naruto. By adding oro's edo, snake summons, snake tech, healing shedding, and immorality its just to much.
3. Tsunade is overkill. The sannins easily would win.
Kisame would struggle against oro and tobirama. Itachi already knows he cant beat jiraiya.
We can never be sure if Itachi was just protecting Konoha knowing that whatever he said, kisame will just follow.
How did Kisame and Itachi know they couldn't beat Jiraiya if they never fought him??? and not only that they said even if they brought more people it wouldn't change which is BS. I take the statement Itachi and Kisame said with a pinch of salt because I think it was a plot excuse for them not to capture Naruto.
that maybe true, but kisame made the comment that jiraiya was on a diffrent league first. So, if anything we can at least say that kisame isnt on the same level as jiraiya.
One thing is funny in this base... that people take the hype for granted when it comes to Madara, Hashirama, Hiruzen, etc, yet when it comes to the hype of the Sannins, people tend to bring them down. I wonder why... Really.
If the hype of one is to be taken for granted, why the hype of other isn't?
In my guess, I say Sannins. They've been renown for their teamwork and abilities.
They know each other for such a long times and they've had hundreds of missions together.
They didn't became feared around the world for nothing.
It not a fairy tale,just think that he will have more stamia just like in Edo form but the body is not invicible.
And just like i said Itachi can use Tsukuyomi on the three Sannin since he is healthy. And don't forget Amaterasu or Susanoo.
Edo gives you unlimited chakra. Nagato was sick and his chakra was still enormous, so I don't think it would make much of a difference if Itachi was healthy. He could only use a few MS techs and a few minutes of Susano in the manga. He would only gain another couple minutes in Susano or one more MS tech if anything. That's still not enough for edo senju brothers who would have unlimited chakra. Couple that with Oro and Tsunade on Kisame and J-man helping against Itachi.
OT: Katsuya slugs could be on all of them to break genjutsu, and like I said if Itachi uses Susano he would have extreme difficulty sealing the brothers while they are spamming big mokuton and water techs. Even if he did seal them, he would almost be running on empty. Then he would have an SM J-man with full stamina to deal with. I see Kisame lasting longer than Itachi though. After J-man is done there they would triple team him and it would be over quickly.
Sanin mid-high diff