The only thing Sakura could do to beat Kakashi is flash him
And to think of it....all they got to do to beat Sasuke is have Konohamaru do his Sai/Sasuke sexy jutsu in front of him...and while Sasukes jaw is on the floor, Rasenshuriken from behind. BAM, Beaten Sasuke till Karen heals him once, then Jugo, then probably Sakura cause of her thing for him, then he'll take a special pill ala a Senzu Beam in DBZ, then cast Susanoo on himself, do the Contra Extra life code and THEN MAYBE he'll lose.....
But probably not... "Amaterasu".....village burns down. Goes to VoE and fights Naruto, "Amaterasu", 9 tails breaks free, "Amaterasu", 9 tails dead, "Amaterasu" Sasuke misses for once, goes blind, Naruto hugs him and tells him to take Itachi's eyes that Naruto somehow aquired, which Sasuke does, says "Thanks"......"Amaterasu", Naruto dies. Sasuke walks around the world casting "Amaterasu" on everything, till he slips, falls, and breaks himself out of a Genjutsu and finds himself all the way back in the Academy classroom with Naruto trying to pass the exam. He'll smile and say "Hey Naruto, let me help you with that!" Credits role, end of series.
(I think I got a little carried away with my sarcasm. It's Kishi and his damn "Amaterasu" crap heheh)