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As a hunter, Kidōmaru is automatically a long-ranged fighter. Using his webs, he
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Also, he has a significant role to combat fighters, such as Jirōbō and Sakon, as he can attach web to them and warn them twitching a part of their body when danger appears.
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Trying to breake it by force is not considerable, as it can support elephants. Once she is trapped, he can activate his Curse Mark.
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After the binding, she has no place to move to. He can finish her with his tendril arrows.
Support: To make it an absolute bind, Tayuya can activate Mateki to bind her absolutely. Kidōmaru can shut his ears with webs in order to prevent hearing the melody. Jirōbō can use CM V2, and compete with Tsunade in means of strength.
If necessary, he can trap her with
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to buy time for Kidōmaru and Tayuya to hide.
It doesn't matter if Sakon and Jirōbō get affected by Genjutsu, since it only binds.
This is game over for Tsunade.