The SO6P's hair is red which clearly defines why the Uzumaki is distance related to the Senju or Uchiha. Since the father have yet to be shown, we can conclude that the red hair trait is from his father. Kaguya is also confirmed to have Byakugan, which means that the Uzumaki and Hyuuga clan existed long before, thus Uzumaki and Hyuuga being descendants of SO6P's brother is void
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