With Neji's battle/chakra intellect and Byakugan plus Rock Lee's Gates, they easily stomp. Why else would Kishi leave out Team Gai during Pain Invasion knowing they would own because Kakashi is too much of a chump to unleash his full Ninjutsu abilities? Neji would easily be able to decipher the abilities of the Six Paths watching the way their chakra flows and aim to obliterate their Chakra Points while Rock Lee would just go gates and go nuts.
Asura Path gets smashed to pieces by Lee, probably even destroying him with his own missile after grabbing it in mid air.
Animal Path would get taken out by Lee or Neji, though would have a difficult time against the dogs
Human Path gets a one panel Leaf Whirlwind by Lee
Naraka Path gets a one panel Palm Rotation by Neji
Preta Path gets his chakra blocked by Neji or if absorbed, gets a Foddara Uchiha bisection by Lee
Deva Path gets butthurt and uses Shinra Tensei only for Neji and Lee to use Filler Style: Primary Lotus Palm Rotation to tank it. Tries using Chibaku Tensei but Lee goes 5th Gate and breaks out of it with Neji using Palm Rotation again and fodderising the Sage
ROCK LEE AND NEJI FTW