Well more like would Minato be defenseless against Shisui's genjutsu or would Minato's FTG/w kunai be too much for Shisui to handle? Despite Kabuto's intense speed he was defeated by Izanami? I don't know if Shisui's particular genjutsu works like that. It was said that both Itachi and Shisui were especially gifted with powerful genjutsu. Itachi was able to use genjutsu on Naruto just by him looking at Itachi's finger? I'm curious for what others would have to say?