1. Hashirama Senju Vs. Uchiha Madara = +1 Senju (already beat him)
2. Tobirama Senju Vs. Uchiha Shisui= +1 Senju/ Draw (depends if shisui's eye is on cooldown
3. Uzumaki Naruto Vs. Uchiha Sasuke= +1 Senju (obviously)
4. Uzumaki Nagato Vs. Uchiha Itachi= +1 Senju (no Kota Amat. means no getting out of chibaku tensei)
5. Tsunade Senju Vs. Uchiha Obito(Let's use Kakashi)= 1+ for senju (she is invincible if she releases her yin seal)
IN Conclusion
Senju =4 or 5
Uchiha = 0 or 1
WINNER= Senju (obviously)
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hashirama never beat madara only in your dreams.
naruto and sasuke are equals andin eveary fight sasuke baiscally wins
shishu has genjutsu totakecontrolof the hokage