Whether or not Tsunade > Sakura, at this point, is arguable. Yeah, I think current "could" (not saying she "would") beat SM Naruto.
She babyshakes pre-powerup Sasuke, as well.
there is no way shape or form that she would be able to beat naruto. i think you have forgotten eactly what sage mode does, let me remind you. you gain access to natural energy, heightened durability, greater speed, sensing, frog katas and precog abilities. so not only is naruto way faster than her but his reflexes are leaps and bounds ahead of hers. how would she even hit him? she not fast enough to dodge a FRS on a consistent basis, and if he throws a huge one she's definitely not dodging. as far as regular rasengans, she could survive those thanks to the byakugo seal. but there is no way for her to survive a FRS, and don't say she can punch it, because that would just kill her.
as for her against sasuke, how does she get past his susano and/or amaterasu? she doesn't have enough speed to dodge it or enough force to break it completely. she may be able to break a rib or something, but a more complete version of susano she cant do $hit against. she literally gets done in by an amaterasu arrow. i'm sorry, but there is no situation were she is on their of their levels. you forget that even before they got their god power-ups, they were the two strongest ninja in the world already. the kage even paled by comparison, only the likes of the edo hokage, obito and madara were comparable.