Orochimaru could take on Kurama, he even could've held his own against Obito [slim chances] but that incident was Obito + Kurama and I son't think Orochimaru who lacks S/T could've done what Minato did.
However if you change the opponent then perhaps Orochimaru can do even better! It all depends on match-ups
orochimaru could never use senju dna back then or even now until he took zetsus body as he never finished his experiments and he didnt get the dna from yamato as i believe orochimaru thought none of the experiments survived