Ondochousetsu (Temperature Control) - Xicer & Klad

Nathan

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The normal body temperature (which varies between 36°C and 37°C, or 96°F and 98,6°F) is a very important aspect of the body, because when the temperature is other then normal, the organism can't work properly (the more it deviates from the normal values, the more the metabolism gets hindered). Normal temperature is needed for all enzymes to work properly and all proteins to exist in their normal state (non denatured, denaturing is a process where the structure of a protein gets irreversibly destroyed and the protein becomes unusable).

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Homework:

Questions (Answer these after reading the article):
  • -Which part of the body initiates the increased tempreature, and how does it happen (On the cellular level)?
  • -Why do we get fevers?
  • -Why do we feel chills after getting a fever?
  • -Difference of a Bacterial and Viral induced fever?
  • -Difference between 'Hypothermia' and 'Hyperthermia'
 

Klad

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1. The brain holds a specific part which is called Thalamus. To explain this on a cellular level, a substance called Pyrogen (produced by a bacterium). The pyrogen, when released in the blood causes the temperature to rise.

2. A fever can be considered as a defensive mechanism of the body in order to fight bacterial infections or diseases. Whenever bacteria or virus enters the body, the immune system produces pyrogen and after it is released does what I stated above.

3. Chills happen because the neurons that are in Thalamus, are set in a higher temperature, lets say 38 celsius. However, the real body's temperature is 37. So, because the genuine temperature is lower than what they are set to, we feel the cold/chills.

4. Bacterial fever is caused by bacteries, and can be fought with antibiotics. Viral fever however, does not go down with antibiotics.

5. Hypothermia is when your body temperature is lower than usual, and hyperthermia is when it is higher than normal.
 

Xicer

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1.) The hypothalamus is responsible for regulating body temperature, so any change has to start there. A pyrogen (or any fever triggering protein) causes the creation of PGE2, which causes the hypothalamus to begin temperature raising processes all over the body.

2.) Depending on the type of infection or condition that is causing the fever, it could be good or bad. Certain metabolic processes are sped up by the increased temperature, which speeds up the healing process. Things such as increased speed and production of white blood cells, and hindering endotoxins effects. But there are certain bacterial infections that actually thrive in the increased temperature, making the sickness harder to get rid of.

3.) We feel chills because the hypothalamus is telling our bodies, 'Look, we need to raise the temperature in here' and until your body reaches the temperature it sets, you will feel cold, while to everyone else you are burning up.

4.) So after reading through the Wiki page, an old text book, and a couple online articles by Dr. Young, a physician studying fever, all that I'm seeing is there isn't a difference. Both bacteria and viruses can release the pyrogens that cause fever. It happens in almost the same way, with the biggest difference being that the pyrogen usually lies within the cell wall of bacteria. Most will get better by themselves, but with the bacterial infection, antibiotics is an option if the infection becomes bad enough.

5.) The answer lies in the words themselves.

-Hypo: Under
-Hyper: Above
-Therm: Temperature
-Ia: Pertaining to

Therefore Hypothermia is the condition pertaining to a lowered body temperature, while hyperthermia is the condition of having a raised body temperature.
 

Nathan

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Good, good. Little more detail for you, Klad. That'll be for the next test.

There are many factors that can disrupt the human bodies temperature; environmental exposition, internal processes (infection, reaction to a poison, etc) or maybe chakra dis-balance. Even extreme physical exertion can destroy enough muscle to trigger an inflamatory rection that will trigger fever. There are various ways to regulate body temperature based on it being high or low, the cause and how far it has risen or dropped. In this skill, you'll learn a few techniques that serve to lower or raise the body temperature. However, this effect is temporary. You'll need to tackle the condition that triggered the change in body temperature and, when that takes time, you'll need to add medicine to help keep the temperature controlled.


Basically, there are two ways this can go: your body temperature will either be too hgih or too low:


Hypothermia occurs mainly due to environmental influences (i.e. when someone isn't dressed appropriately, when someone falls into cold water, gets buried in by snow etc.), internally it can mean damage to the TRC (look below for what that is) or it can also be caused by overuse of the temperature lowering techniques I posted below; and that is why I made that chart, and that is why you have to learn the values .
To counter hypothermia itself you can proceed in 2 ways; one would be using fire chakra (to heat the patients body, not to burn it!! be careful) or to use this tech:

(Iryō Ninjutsu: Rinkai Roppou) Medical Technique: Temperature rise
Type: Supplementary
Rank: B-Rank
Range: Short
Chakra: 20
Damage: N/A
Description: The user will place both of his hands on the patients body, and insert a fair amount of his chakra into the patient. He or she will then will/make the chakra affect the heart (fastening the heart rate), the blood vessels (constricting them rising the blood pressure) and the thyroid gland (inducing faster release of hormones that enhance the metabolism). As result the body temperature will rise to 37°C (or 98,6°F).
Note: user must be a master of Diagnosis

Sub-febrile temperature is, in most cases, just a symptom of a rising infection/upcoming illness. It is important to not lower this temperature because it actually helps the body fight the disease! The rise in temperature is caused by the body in a complicated way, but I will try to simplify it a bit in a few steps:
1. An infection or a strange substance triggers the detection/production of an antigen (as viruses, bacteria, poisons etc.).
2. The antibodies react to the presence of that antigen by attacking it, but first they release mediators. Mediators (histamine for example) are chemical substances that notify the entire organism of the presence of an antigen.
3. Mediators reach the center of thermal regulation (which is located in the hypothalamus) and signal that an antigen was detected.
4. As a result, the TRC (thermoregulation center) rises up the temperature by more or less 0,5°C (that is about 0,9°F) by sending off hormones that tell the pituitary gland to release the TSH hormone which controls the thyroid gland, which in turn releases T3 and T4 hormones which enhance/speed up the overall metabolism of the person, which, in turn, is what is really needed to achieve the rise in temperature. Temperature rises by increasing blood flow, metabolic functions and by burning calories. Shivers, for example, are a way for the body to use the muscles to burn calories through involuntary movements which in turn produces heat.
5. The slight rise in temperatures activates more and more antibodies and enhances their performance as well as further increasing blood glow and circulation which then further increases the response of the organism.

Febrile temperature comes in place when the previously mentioned antigen continues to be produced as a result of a resulting infection, so more and more antibodies get released which in turn release more and more mediators, which then make the TRC go berserk and it totally looses its sense of normal temperature. When this happens, the temperature isn't optimal for enzymes and antibodies in general anymore, and they loose their effectiveness, therefore the effect of sub-febrile temperature is negated, and the state is useless or more often dangerous because at a point the antibody stop working altogether. This is when you need to start lowering the temperature, and you do this by using this technique:

(Iryō Ninjutsu: Rinkai Umou Seppan) Medical Technique: Gentle Temperature Ease
Type: Supplementary
Rank: B-Rank
Range: Short
Chakra: 20
Damage: N/A
Description: In order for this jutsu to take effect, the user must somehow have contact with the earth; be it actual ground or a mere pot filled with earth. The user places his dominant hand on the patients chest, and the other hand on the ground/earth. By activating this technique the user takes excessive temperature from the patient, guides it through his body and releases it into the earth through his other hand. This relieves the temperature of the patient by 0,8°C (or 1,4°F) per use until the patient's temperature is 36ºC.
Note: If unable to guide the chakra into the ground/pot of earth, then the users temperature rises for the mentioned amount

(Iryō Ninjutsu: Rinkai Umou Mattou) Medical Technique: Complete Temperature Ease

Type: Supplementary
Rank: A-Rank
Chakra: 30
Damage: N/A
Range: Short
Description: In order for this jutsu to take effect, the user must somehow have contact with the earth; be it actual ground or a mere pot filled with earth. The user places his dominant hand on the patients chest, and the other hand on the ground/earth. By activating this technique the user takes excessive temperature from the patient, guides it through his body and releases it into the earth through his other hand. This relieves the temperature of the patient by 1,6°C (or ~3°F).
Note: If unable to guide the chakra into the ground/pot of earth, then the users temperature rises for the mentioned amount


Make sure you don't lower the temperature too much (below sub-febrile) because you want that effect it gives, but then again you need to lower it enough to not be dangerous anymore. You'll perfect this with practice .

Very high febrility is when it becomes lethal. The temperature is now higher then the protein structure can stand, and they begin to disintegrate, denature and become useless, this means actually tissue is dying off! And of course, the most effected by this is the brain. At this moment don't think about getting to the optimal temperature, lower it by any means necessary; be it water jutsu (of low rank, you don't want to hurt the patient) or even ice jutsu. Of course you can not use a jutsu and got for the old fashioned way of putting him/her in a bathtub full of ice cubes. Your main goal is to save life here!

This has some cientifical knowledge here but the main aspects to rettain for NB RPG are these:

-All large wounds and trauma will always induce fever due to either the inflamatory reaction to the tissue destuction or the infection caused by large open wounds.

-Toxins, Venoms and Poisons will always rise the body temperature before dropping it abruptly unless its defined in the toxin, venom or poison description as otherwise.

-Blood loss will always lower your body temperature and bring about a state of hypothermia, severe or not.

-Chakra depletion will lower your body temperature.

Any questions?
 
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