Hey that makes sense, because he told Sasuke if he attacks Konoha he has to kill him first, and Hokage is the perfect person to confront somebody who wants to kill the village. Except there is a problem, that in the same confrontation where he told Sasuke this he also told Kakashi that he can't be Hokage if he can't save one friend. So it'll definitely have to be before he's Hokage. Tsunade doesn't have to die for this, she could still survive and decide to retire.
thats just naruto BS , kashi is just missleading the fans , think about it ,
if i cant save one friend how can i be hokage
if we both fight , wer're going to die
im going to be hokage no matter what
i wont let you guys down (to his parents )