When Sasuke fought Orochimaru, Orochimaru was almost dying and waiting for a new body..., even Sasuke aknowledged that he managed to defeat Orochimaru because of that.
And on the other case, Itachi could have beaten Sasuke if he'd wanted to, but that wasn't his objective. Itachi was a guy with an illness that was in its terminal phase, and he should've died a long time ago, but he grasped to life just to encounter Sasuke again, so that he could free him from Orochimaru and give him his mangekyo powers to protect him. During the fight Itachi restrained hisself from using excesive force against Sasuke (look at the last shippuden chapter and you'll see how he stopped Amaterasu willingly so that it wouldn't harm Sasuke when they clashed with their fire atacks), and in the end of that figh Itachi managed to leave Sasuke out of chakra so that Orochimaru could come out, and when it happened Itachi got happy and said that he'd been waiting for him to come out...., and killed him with Susano. The thing is that a dying Itachi would've been able to kick Sasuke's ass if he'd wanted to..., can you imagine what Itachi was capable of doing while being healthy?
That's why, please, stop saying that Sasuke beat Itachi and Orochimaru just like that, because if any of them had been in top shape, Sasuke wouldn't have stand a chance against them (he didn't even stand a chance agains a terminal Itachi).
About this chapter I think that Kisame, or at least Samehada aren't finished yet...; did anyone notice that Samehada was winding itself on KB's arm when Raikage arrived and Bee was still on the floor (look at the cord with the skull on its end), and that previoulsy, when Bee's singing master was runing through the forest he stumbled with Samehada.
I agree with those who say that Kisame's death is mysterious.