it doesn`t matter if she is a senju or notIf Tsunade had an affinity for earth and later developed one for water (or vice versa), would she theoretically be able to use moukton even though her dna is only half senju?
I don't quite understand this one, shouldn't dust release beit doesn`t matter if she is a senju or not
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of course she can
EDIT: actually this1 is better:
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oro experimented on sooooo many childes(not only yamato) and Only one of them turned to be a moukton user .There is a possibility.
If Orochimaru created Yamato by using Senju's cells and he can use moukton, then theoretically if Tsunade were to gain the two attributes water and earth she could have inherited the genes for the technique.
I guess we'll never know though >)