Nail Mei- if a child was produced then kid would have Fire, Earth, and Water release which would be awesome!/ I wouldn't have the mother after me until I die of old age.(no uzumaki) plus she is the Mizukage if i married the Hokage then she couldn't do anything to me if I wanted out.
Marry Tsunade- She is the Hokage of the Fire country (im sure husband would have some serious benefits); has awesome healing techs to keep me healthy and I would get to be with 2 Kages because of above reason. Then when I go to kill Kushina (assuming she is somehow okay with this) She can teach me Healing techs, Uzumaki seals, perfect chakara control, how to enhance my strength, and various toxins to help aid me in killing the Jink./ fending off being melted by Mizukage if that relationship went south.
Kill Kushina- Bossy lady with weird sayings and would always be weird because the Fox is always hanging around so technically it would ALWAYS be a threesome... with a beast.... But I don't like the idea of trying to kill the 9 tails Jink. 1.)She was really powerful uzumaki. 2.) She would enhance the leaf's military power.