In terms of chakra. Base madara has more chakra reserves than base hashirama. Lets not forget that perfect susanoo is a tech of base madara, base hashirama has nothing that can compete with that. which is why the instant madara pulled it out at the vote, hashirama ran and was on the defensive. It took him SM which is an external augmentation of chakra to beat ps and compete on the same level. However, w.o sage mode there is no tech that the first possesses which can compete with ps's destructive power.