No, they won't... They just fight to figure out who gets which of her halfs xD
On a more serious note, one of the running theme's in Naruto seems to be that nice guys finish last, and girls go wet for the douches... Which, for a change considering we're talking of orange-clothed ninja protagonists who go through a world of bloodshed without killing anyone, goes just as in real life.
We have Sakura and Naruto, Jiraya and Tsunade, Obito and Rin... Hell, I wouldn't even be surprised if our current anti-villain, Madara, was actually a fairly nice guy who had the hots for Mito, though she wanted nothing to do with him and was all eyes for Hashirama, who was in fact a complete douchebag (in spite of the good guy rep), which in turn resulted in Madara, who was probably the most powerful ninja since god knows when, deciding to "fix" things in a way that resonated with his power level, that is, rewiring fvcking reality (lol, talk about heartbreak).
I wouldn't put it past him.
Anyways, I don't think Tsunade had any feelings for Jiraya... She probably only said that line about his tough face in order to see if he would rise from the grave... I'm actually wondering how come he didn't.
If anything, I think it's more likely that Sakura will die than marry beta-male Naruto... Which is just fine, really. I wouldn't want leftovers if I were Naruto.