I say Onoki and Tsunade takes this. If it's manga knowledge then Tsunade knows about Itachi's genjutsu capabilities among other skills he uses a lot.
Tsunade can keep Itachi busy with taijutsu while Onoki launches a jinton.
Tsukuyomi won't really be a problem, amaterasu could be one, for Onoki but Tsunade can deal with it.
Tsunade can keep Itachi busy with taijutsu while Onoki launches a jinton.
Tsukuyomi won't really be a problem, amaterasu could be one, for Onoki but Tsunade can deal with it.