Itachi and orochimaru win this
--With the starting distance of 20m, Itachi can set kisame ablaze through amaterasu, as he is too slow to evade the flames or react to the attack and his samehada wont be able to absorb flames this hot as well
--Kisame also gets taken out by the totsuka blade, or tsukuyomi, seeing how the genjutsus effects are too fast and itachi can land this quite well through the use of crows, and orochimaru acting as a diversion, who can tank their attacks quite well even if he gets hit in the process
--Orochimarus regeneration and snake skin enables him to counter tobiramas attacks quite well, as he summons manda who tobirama has no way of attacking at all, summoning manda also enables itachi to not overuse his MS therefore he wont be running out of chakra that easily,
--Tobirama has no way of taking down manda or hydra as both of them bypass his limits of FTG by destroying all the marked locations, as the duo can then finish tobirama off rather easily
--With the starting distance of 20m, Itachi can set kisame ablaze through amaterasu, as he is too slow to evade the flames or react to the attack and his samehada wont be able to absorb flames this hot as well
--Kisame also gets taken out by the totsuka blade, or tsukuyomi, seeing how the genjutsus effects are too fast and itachi can land this quite well through the use of crows, and orochimaru acting as a diversion, who can tank their attacks quite well even if he gets hit in the process
--Orochimarus regeneration and snake skin enables him to counter tobiramas attacks quite well, as he summons manda who tobirama has no way of attacking at all, summoning manda also enables itachi to not overuse his MS therefore he wont be running out of chakra that easily,
--Tobirama has no way of taking down manda or hydra as both of them bypass his limits of FTG by destroying all the marked locations, as the duo can then finish tobirama off rather easily