1. Orochimaru doesn't want radical change thoughOfc it's the same and what you don't get is base on what I make this comparison. It's like you hating your father as a kid and yet you end up just like him even though you thought he was so wrong. I'm not simply pointing the similarity in desiring a "change", I specifically talked about how Sasuek thought so low of Orochimaru at first and yet he ended up also desiring a complete, radical change. This comparison also goes to show how Sasuke's mentality changed over time since when he first went to Orochimaru, he didn't want to kill people and in general he was more reserved as to how he would act whereas now he's willing to kill anyone and with whatever means, be it moral or immoral, just to complete his aim, much like how Orochimaru became ruthless when he became obsessed with his dreams.
You see it from a very narrow perspective, it's not only about the change, it's how the 2 of them begun, and how sharing the same dream in some extent, albeit Orochimaru's was one of many and not that specific, made his student adopt some of his traits of his personality.
2. Sasuke was opposed to Orochimaru's ways not because he was against killing, he was against killing people that had nothing to do with what he was doing, Sasuke was opposed to killing innocent people and toying with life, which Orochimaru did. The only time Sasuke was like that was at the Kage Summit, and even then it could be argued that since the Samurai attacked him first, it was just self-defense and doesn't technically violate his principle, but his mental instability at the time makes that call less likely.
Back then, Sasuke was willing to kill people if there was a justifiable need. Since Sasuke sees killing the Kages and Naruto as a step towards a better world, it's a justifiable need. Orochimaru experimented with lives for his own selfish purposes, not to bring about a radical change, so no, they are not on the same parth.
I find it funny you're saying I'm looking at this with a narrow mind, but I'm focusing more on the individual details than you actually are.