Be realistic kakashis and obitos death are going to have to occur
Have Naruto and Sasuke accidentally kill Sakura when she gets in the middle of their battle and have everyone who died be revived (Shikaku, Inoichi, Neji, Itachi, Nagato, Yuhiko, Konan, ect) only Sakura can't be revived due to something in her blood cells that suppresses a reanimation jutsu. That would be pure gold.
First, make Oro the main villain again. I don't care for the rest.