Not that much of a problem if you hit a body component with gentle fist that you didnt intent to hit.It's cause chakra scalprel is deadly whenever Kabuto touch it can kill any body component so he just feel where to strike at, not the same case with the gentlefist when there are many organs which is hard where to strike
You still do internal dmg to your opponent. You still use gentle fist.
You can use Gentle fist, without attacking the tenketsus.It is essential where to strike at, without it, it will lose alot of effectivness, and it's impossible to hit all the tenketsu without the byakugan, Bolt is just gonna randomly strike to get atleast some luck.
The tenketsus are only a part of the Gentle fist.