Yeah. Don't think anyone can come up with any formidable points in favor of it.
There were hints that they could end up together, but you look back at their relationship from scratch, Sakura's feelings were always unreturned. The only thing that Sasuke did that could be considered endearing was when he poked her forehead when he left the village.
After that, we only got to see Sakura perfidiously trying to kill Sasuke, and Sasuke reciprocating his ardent feelings for her (which were hate and irritation) by using her to get Danzou.
Every time we reminisce about those two there's never quite anything that suggests that Sasuke even secretly reciprocated those feelings. And when he showed kindness towards her after his final fight with Naruto it couldn't be one he could have given her if he wasn't sympathetic over realizing how he kept on rejecting her at every chance. The mere fact they got together was because Sasuke felt he "owed' her just as he felt indebted to the village and ended up travelling the world. That's how he was atoning for his sins.
So his relationship with Sakura was only possible because of Sasuke's realizing that he had hurt her and was therefore in some debt he needed to pay. In which case, his sperm was found injected in her eggs so Sakura could get what she always wanted, and thus the weight of his sins would diminish. Not that she didn't want to relish the process.
To me, Sasuke was always that solo ninja who didn't need females around him. He had skillful hands and was naturally reclusive. Company to him was only for important moments. Sakura, in the other hand, was a luquacious beach who just wanted to use him for her fantasies, all built up around Sasuke sliding into her parched Gate of Diablo.