Explain how they deal with the pollen from his forest if he summons it a couple of football fields distance around him in every direction. Or if he uses his chakra absorbing moukton to shield himself from them. Or explain how they fatally damage him in any way when he heals with no seals and has better healing than Tsunade who can tank getting bisected. There is just no way they can win.
He has no feats of healing better than Tsunade and certainly nothing to suggest he will survive being bisected... lol.
Tobirama cut God Tree branches with his Water Style and Minato cut them with no arms (presumably a Kunai in the mouth) so his pollen plant gets totally chopped up especially when we consider that the God Tree's branches >>>>>>>>>>>>>>>> Hashirama's in terms of size and power.
They can just play tag with him. He has no speed feats that put him even remotely close to their level, movement or fight speed. Both of them can blitz him from 40 meters and the fact they can make clones who also use Hirashin makes this even worse for him. He has no feats of making a forest faster than they can shunshin or teleport to him and once that happens its
literally over because he gets marked before he knows it with Tobirama and Minato insane reaction and fight speed and from there they swap his ass around gang-banging him to no end and he
can't react to it, there is literally zero chance, hes done for, swapped again and again before he even realized he was swapped twice already while being bombarded by their attacks from their clones. Or they just make it quick and decapitate him.
Theres also Ma + Pa and when Minato summons them (which it does not even have to come to) its game over.