Yes and no. When you look at his intelligence level, ability to break down every battle scenerio, analyze, speed, inhuman hand sign speed, genjutsu proficiency above anyone we've seen, and all of his god-like techs his MS granted him
But on the flip side he was suffering and dying for almost 10 years from a deadly disease that pretty much shot his stamina to the lowest possible level....which means he doesn't do great in a long drawn out battle
On the other hand, to compensate for that weakness he has in his arsenal some of the most powerful jutsus that allow him to one-shot his opponents. None of his battles went longer than he wanted them do. Itachi was like the perfect chess player.
But still, while alive his disease was Kishi's way of keeping Itachi down to earth