IMO,I would take the Uchiha villains over the boneheaded Otsustuki any day
the story Otsutsuki clan is much much much more interesting than the Uchiha , it explains the existence of chakra and and the doujutsus and also the KKG , and it also explains the creation of Ninjutsu
the story would've been much better if it was focused on the Otsutsuki and the NV ,
but since the manga was revolving about a f*cking yaoi relationship between Naruto and Sasuke , and since "dear" Sasuke is an Uchiha , Kishimoto needed to give him an overpowered abilities so he can keep up with Naruto
(BTW , I admit that the Otsutsuki villains were lame , but I am just saying that Kishi should've focused on them from the start , instead , he made the main villain showed up before 22 chapter from the end of the manga , which is really lame)