Welll this certainly is a plausible thread yes indeed but there are holes. Well for one Sakura and tsinade are not yin affinite they are yang affinite. Yang is physical energy which is what tsunade and Sakura and charging up not their own tin so to speak such as gai's gates, that's yang it real eases power just like tsunade and Sakura.
Sasuke doesn't need to use it more than once, why would he? If his opponent is right there than there is no need to hassle. HOWEVER here comes the boom.
remember when madara was juubidara? How he flees from sasuke claiming to know his eye's extent. Well sasuke caught up to madara faster than he should. Madara covered a large distance and we know that juubidara is incredibly fast. The approximate distance between sasuke and madara by the screens was probably lot of yards. By the speed sasuke caught up to madara and sasuke normally isn't as fast as juubidara, he'd have to use the technique more than once.
however using the technique more than once most likely drains him, that's why he needed to close his eyes to conserve unlike with kaguya or when he swapped the sword like with madara he didn't need to close his eyes. Plus the eyes are still new so sasuke is still adjusting to them, that could be another factor.