Naruto's Senjutsu boost isn't large enough to let him tank his strongest move from before his boost, which would be his Flash Bijuu Dama. So Minato can hurt him, it'll just take time. If Minato marks him, which will easily occur if they engage in Avatar to Avatar combat, then Minato can warp Naruto's own attacks (or his own) right onto Naruto's body to prevent him from defending with his tails.
-Can't use a vast amount of clones if he wants to use his Avatar.
-Not sure how his vast amount of clones are supposed to counter anything Minato does while in Bijuu Mode.
-There is a benefit. A strength boost. The size of it isn't as large as people would think so in this particular scenario it doesn't help him.