Whether he uses it out in the open or not doesn't change the fact that Continuous Bijuu Dama will effortlessly destroy the sphere. If he uses it, it has to be in range of Killer B so the gravitational pull can drag him up. When that happens, B fires his Continuous Bijuu Dama at the sphere and the gravitational pull will pull the attack straight to the core like
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Preta Path can absorb a TBB if its fired at him, but this will be fired, up in the air, at the sphere, so no Preta isn't stopping the sphere from being blown up.
Yes we did just argue this.
Human Path is useless as it can't touch B (Who is cloaked in Hachibi's chakra) to pull his soul out. Not to mention it'd get wrecked with ease if it even got anywhere near him to attempt to pull his soul out.
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followed up with Continuous Bijuu Dama ends every Pain except for Preta Path, who can absorb the part of the explosion that it touches. (Don't say it'll intercept the Bijuu Dama for the other paths, because it won't be able to do so when its getting tossed back by an attack that leveled a forest.
B takes this mid diff.