Exactly. One of the main themes of this story is the generational continuation of the ideals and strengths of the elder shinobi. Tsunade is old and it's time for the will of fire to go on to the next Hokage ( probably Naruto). I just can't wait for that perverted freak Orochimaru to finally meet his end, for real this time.Yeah I think so, i honestly think that by the end of the series all 3 sannin will be dead.
wat MR SIMPLE says is what i say ahaDid you see it, didn't you? Tsunade is into pieces... but i'm not sure if she trick him that she's already dead or Madara let her to die in agony...
It's plot no jutsu.Well Tsunade can still move and summon, so it must not be that bad haha.
If you look at it, main parts aren't destroyed (heart, brain).It's plot no jutsu.