He would beat him without edo tensei.
IDK about that, hes giving him a pretty hard time with Izanagi right now.
And thats with the Sasuke handicap!
Why would Sasuke be a handicap? How many times would Itachi have been killed if he wasn't an edo tensei?
None of Itachi's MS techniques would work on Kabuto and he would have been finished with that genjutsu used by Kabuto.