I'm voting for Tsunade... Note Kakashi is a swag beast, but maybe DESTROYED by Tsunade if one power packed punch is delivered directly towards him. people rant on about how kamui will be a key factor in kakashi's victory, yet no one is taking into account tsunade's monstrous power which ACTUALLY HAS ACCURACY COMPARED TO KAMUI. kamui is a joke, powerful but has little accuracy and uses 1/3 kakashi's chakra. fanboys argue that kakashi's chakra has risen to a point where he can use 6 kamuis, what ludicrous rubbish that I am hearing. kakashi amitted that had he used kamui against kakuzu he would have been in the hospital bed, note, this was not too long ago during the kakuzu hidan arc that if kakashi used one meesly kamui he would have been hospitalized, what to say had he used 6 kamuis like some fanboys claim.
lightning blade and raikiri will be virtually effectless, tsunade tanked two stabs from the kusangi blade and healed like nothing, im sure she can be impaled by lughtning blade without being killed right away.