So its been speculated that only Madara (and now Sasuke if they ever get back to him) had an EMS. However
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{the bottom panel}
Makes you wonder if there were other EMS users. Also wouldnt it be crazy if one of them came back with Edo Tensi so we can actually see what an EMS can do.
Thoughts?
This is a very good point, I myself recently read this panel again for reference and noticed the same thing. My initial reaction to reading this panel again is that the statement was used some-what as an expression, to kind of accentuate the Uchiha clan's bloodlust and need for power and didn't accurately depict reality. With that, it seems very doubtful to me that the statement is 100% false.
I have to say, that it makes perfect sense that after Madara left the village, others within the clan attempted to follow in his footsteps and obtain the EMS power. Clearly, since Madara obtained it, it was within the power of all the clan members to accomplish. Its also clear that they all had access to this information via the Uchiha tablet, but Madara was simply the first to act on it.
Bottom line....I think there were, at the very minimum, attempts to attain EMS by clan members after Madara left the village. It seems plausible to me that one or two did obtain EMS after that point, as the statement suggests. However, if someone or multiple people did obtain it, they clearly played no major role in any affairs leading up to the massacre. Everyone has stated that Tobi has to be Madara because he is the only one who could have possibly done all of this, so no Uchiha was ever more powerful than him. In addition, Itachi never referenced anyone beyond the base 4 (himself, Madara, Izuna and Sasuke) as having MS. So while it is plausible, it is clear that if others did obtain it, they are not on anyone's radar; Madara, Itachi and Kabuto included.